|کد مقاله||سال انتشار||مقاله انگلیسی||ترجمه فارسی||تعداد کلمات|
|131067||2017||15 صفحه PDF||سفارش دهید||3242 کلمه|
Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)
Journal : Neuroscience Letters, Volume 639, 3 February 2017, Pages 162-166
A mouse model of traumatic stress provided insight into a mechanism of individual differences in conditioned fear responding. Hippocampal serotonergic activity (metabolic turnover) was associated with increased behavioral freezing during fear acquisition in a portion of trauma-exposed subjects. These subjects later displayed enhanced fear to the neutral cue during retention. An inability to discriminate fear responses may underlie dysfunctional fear memories in a sub-population of individuals with Posttraumatic Stress Disorder, with contributions from the hippocampal serotonin system.