دانلود مقاله ISI انگلیسی شماره 35738
ترجمه فارسی عنوان مقاله

آنتاگونیست هورمون آزادسازی هورمون گنادوتروپین در موارد انحراف جنسی شدید: درمان طول عمر؟

عنوان انگلیسی
Gonadotrophin hormone releasing hormone agonist in cases of severe paraphilia: A lifetime treatment?
کد مقاله سال انتشار تعداد صفحات مقاله انگلیسی
35738 1996 9 صفحه PDF
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Psychoneuroendocrinology, Volume 21, Issue 4, May 1996, Pages 411–419

ترجمه کلمات کلیدی
مجرم جنسی - انحراف جنسی - تستوسترون
کلمات کلیدی انگلیسی
Sex offenders; Paraphilia; GnRH-a; Testosterone
پیش نمایش مقاله
پیش نمایش مقاله  آنتاگونیست هورمون آزادسازی هورمون گنادوتروپین در موارد انحراف جنسی شدید: درمان طول عمر؟

چکیده انگلیسی

Six patients with severe paraphilia were treated with a long-acting gonadotrophin hormone releasing hormone analogue (GnRH-a). In five cases, the antiandrogen treatment ended their deviant sexual behaviour and markedly decreased their sexual fantasies and activities without significant side-effects. The beneficial effects of this treatment were maintained for 7 years in the patient where there was the longest follow-up. Two patients abruptly withdrew from their antiandrogen treatment at the end of the first and third year, respectively. Both relapsed within 8–10 weeks. One of them asked for resumption of antiandrogen treatment. In another case, in order to phase out antiandrogen treatment, testosterone (T) was added to the GnRH-a. In spite of normal T levels, and of resumption of normal sexual activities and deviant fantasies, deviant sexual behaviour did not return. A smoother phasing out of GnRH-a treatment is thought to be better than an abrupt withdrawal. However, the duration of antiandrogen treatment necessary to ensure a complete disappearance of deviant sexual behaviour remains uncertain, but is at least 4 years.