دانلود مقاله ISI انگلیسی شماره 39842
عنوان فارسی مقاله

فقدان لذت در اسکیزوفرنی: نقص در هر دو انگیزه و ظرفیت لذت

کد مقاله سال انتشار مقاله انگلیسی ترجمه فارسی تعداد کلمات
39842 2015 10 صفحه PDF سفارش دهید محاسبه نشده
خرید مقاله
پس از پرداخت، فوراً می توانید مقاله را دانلود فرمایید.
عنوان انگلیسی
Anhedonia in schizophrenia: Deficits in both motivation and hedonic capacity
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Schizophrenia Research, Volume 168, Issues 1–2, October 2015, Pages 465–474

کلمات کلیدی
فقدان لذت - علائم منفی - تلاش - انگیزه - اسکیزوفرنی
پیش نمایش مقاله
پیش نمایش مقاله فقدان لذت در اسکیزوفرنی: نقص در هر دو انگیزه و ظرفیت لذت

چکیده انگلیسی

Anhedonia is one of the core negative symptoms of schizophrenia that affect the ultimate outcome of this disorder. It is unclear whether the motivational or the hedonic component of anhedonia is impaired in patients with schizophrenia. This study examined the deficits in motivation and hedonic capacity in patients with schizophrenia using an Effort-based pleasure experience task (E-pet). Twenty-two schizophrenia patients with prominent negative symptoms, 18 schizophrenia patients without prominent negative symptoms and 29 healthy controls participated in the present study. All of them were administered the E-pet task, which required the participants to make decisions on whether to choose a hard or easy task based on probability and reward magnitude. When making the grip effort allocation decision, schizophrenia patients with prominent negative symptoms were significantly less likely to choose a hard task than healthy controls. As the reward magnitude and the estimated reward value increased, unlike healthy controls, schizophrenia patients with prominent negative symptoms did not increase their hard task choices. They were also significantly less likely to choose a hard task than healthy controls in medium and high probability conditions. When anticipating potential rewards, these patients reported significantly less anticipatory pleasure than healthy controls, even when reward probability and magnitude increased. The pleasure experience rating after obtaining the actual reward was positively correlated with two pleasure experience scales in schizophrenia patients. In conclusion, patients with schizophrenia, especially those with prominent negative symptoms, showed deficits in both reward motivation and anticipatory pleasure experience.

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