دانلود مقاله ISI انگلیسی شماره 40168
عنوان فارسی مقاله

بررسی مراقب بهداشتی دارو درمانی برای درمان نقص توجه / بیش فعالی در افراد مبتلا به سندرم ویلیامز

کد مقاله سال انتشار مقاله انگلیسی ترجمه فارسی تعداد کلمات
40168 2013 10 صفحه PDF سفارش دهید محاسبه نشده
خرید مقاله
پس از پرداخت، فوراً می توانید مقاله را دانلود فرمایید.
عنوان انگلیسی
Caregiver survey of pharmacotherapy to treat attention deficit/hyperactivity disorder in individuals with Williams syndrome
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Research in Developmental Disabilities, Volume 34, Issue 5, May 2013, Pages 1700–1709

کلمات کلیدی
سندرم ویلیامز - محرک دارویی - داروهای ADHD - متیل فنیدیت - آمفتامین
پیش نمایش مقاله
پیش نمایش مقاله بررسی مراقب بهداشتی دارو درمانی برای درمان نقص توجه / بیش فعالی در افراد مبتلا به سندرم ویلیامز

چکیده انگلیسی

Williams syndrome (WS) is a genetic condition characterized by a unique neurocognitive and behavioral profile, including increased incidence of attention deficit/hyperactivity disorder (ADHD). The purpose of the present study was to examine the perceived helpfulness and side effects of medications used to treat ADHD (methylphenidate class, amphetamine class, atomoxetine) in individuals with WS. This was accomplished with a survey of parents/caregivers of individuals with WS through the Williams Syndrome Association. Five-hundred twelve (512) parents/caregivers responded to the survey regarding their child's/adult child's use of ADHD medications. Twenty-seven percent (27%) of the individuals had been prescribed a medication for ADHD, most commonly a methylphenidate class medication. OROS-methylphenidate was reported as the most helpful methylphenidate class formulation, with 74% reporting it at least somewhat helpful. Survey participants reported similar side effects as typically developing controls, but to a greater degree. Irritability was the most commonly endorsed side effect of an ADHD medication (38%). Individuals reported use of stimulant medications in the presence and absence of underlying cardiac conditions, with 56% of ADHD medication users reporting supravalvular aortic stenosis, 36% pulmonary artery stenosis, and 25% systemic hypertension. Individuals taking ADHD medications were more likely to report dental problems (p = 0.004). Additional studies are needed to further investigate these findings and examine short-versus long-acting stimulant medications and dosage effects.

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