دانلود مقاله ISI انگلیسی شماره 41256
عنوان فارسی مقاله

اختلال در رفتار اجتماعی دو سال پس از قرار گرفتن جنین در معرض الکل در گورخرماهی همچنان ادامه دارد : یک مدل از اختلالات طیف الکل

کد مقاله سال انتشار مقاله انگلیسی ترجمه فارسی تعداد کلمات
41256 2015 7 صفحه PDF سفارش دهید محاسبه نشده
خرید مقاله
پس از پرداخت، فوراً می توانید مقاله را دانلود فرمایید.
عنوان انگلیسی
Impairment of social behaviour persists two years after embryonic alcohol exposure in zebrafish: A model of fetal alcohol spectrum disorders
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Behavioural Brain Research, Volume 292, 1 October 2015, Pages 102–108

کلمات کلیدی
اتانول - الکل اتیلیک - جنین اختلال طیف الکل - گورخرماهی - رفتار اجتماعی - سن
پیش نمایش مقاله
پیش نمایش مقاله اختلال در رفتار اجتماعی دو سال پس از قرار گرفتن جنین در معرض الکل در گورخرماهی همچنان ادامه دارد : یک مدل از اختلالات طیف الکل

چکیده انگلیسی

Zebrafish naturally form social groups called shoals. Previously, we have shown that submerging zebrafish eggs into low concentrations of alcohol (0.00, 0.25, 0.50, 0.75 and 1.00 vol/vol% external bath concentration) during development (24 h post-fertilization) for two hours resulted in impaired shoaling response in seven month old young adult zebrafish. Here we investigate whether this embryonic alcohol exposure induced behavioural deficit persists to older age. Zebrafish embryos were exposed either to fresh system water (control) or to 1% alcohol for two hours, 24 h after fertilization, and were raised in a high-density tank system. Social behaviour was tested by presenting the experimental fish with a computer animated group of zebrafish images, while automated tracking software measured their behaviour. Control fish were found to respond strongly to animated conspecific images by reducing their distanceand remaining close to the images during image presentation, embryonic alcohol treated fish did not. Our results suggest that the impaired shoaling response of the alcohol exposed fish was not due to altered motor function or visual perception, but likely to a central nervous system alteration affecting social behaviour itself. We found the effects of embryonic alcohol exposure on social behaviour not to diminish with age, a result that demonstrates the deleterious and potentially life-long consequences of exposure to even small amount of alcohol during embryonic development in vertebrates.

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