دانلود مقاله ISI انگلیسی شماره 43526
عنوان فارسی مقاله

مقایسه دریچه آئورت از طریق کاتتر و دوام دریچه بیولوژیکی جراحی: مطالعات شبیه سازی خستگی

کد مقاله سال انتشار مقاله انگلیسی ترجمه فارسی تعداد کلمات
43526 2015 9 صفحه PDF سفارش دهید محاسبه نشده
خرید مقاله
پس از پرداخت، فوراً می توانید مقاله را دانلود فرمایید.
عنوان انگلیسی
Comparison of transcatheter aortic valve and surgical bioprosthetic valve durability: A fatigue simulation study
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Journal of Biomechanics, Volume 48, Issue 12, 18 September 2015, Pages 3026–3034

کلمات کلیدی
دریچه آئورت از طریق کاتتر - دریچه های قلب بیولوژیکی - آسیب خستگی بافت نرم - تجزیه و تحلیل المان محدود
پیش نمایش مقاله
پیش نمایش مقاله مقایسه دریچه آئورت از طریق کاتتر و دوام دریچه بیولوژیکی جراحی: مطالعات شبیه سازی خستگی

چکیده انگلیسی

Transcatheter aortic valve (TAV) intervention is now the standard-of-care treatment for inoperable patients and a viable alternative treatment option for high-risk patients with symptomatic aortic stenosis. While the procedure is associated with lower operative risk and shorter recovery times than traditional surgical aortic valve (SAV) replacement, TAV intervention is still not considered for lower-risk patients due in part to concerns about device durability. It is well known that bioprosthetic SAVs have limited durability, and TAVs are generally assumed to have even worse durability, yet there is little long-term data to confirm this suspicion. In this study, TAV and SAV leaflet fatigue due to cyclic loading was investigated through finite element analysis by implementing a computational soft tissue fatigue damage model to describe the behavior of the pericardial leaflets. Under identical loading conditions and with identical leaflet tissue properties, the TAV leaflets sustained higher stresses, strains, and fatigue damage compared to the SAV leaflets. The simulation results suggest that the durability of TAVs may be significantly reduced compared to SAVs to about 7.8 years. The developed computational framework may be useful in optimizing TAV design parameters to improve leaflet durability, and assessing the effects of underexpanded, elliptical, or non-uniformly expanded stent deployment on TAV durability.

خرید مقاله
پس از پرداخت، فوراً می توانید مقاله را دانلود فرمایید.