دانلود مقاله ISI انگلیسی شماره 67741
عنوان فارسی مقاله

درمان روان دارو شناسی 2195 بیمار مبتلا به اختلال شخصیت مرزی: مقایسه با سایر اختلالات روانپزشکی

کد مقاله سال انتشار مقاله انگلیسی ترجمه فارسی تعداد کلمات
67741 2015 10 صفحه PDF سفارش دهید محاسبه نشده
خرید مقاله
پس از پرداخت، فوراً می توانید مقاله را دانلود فرمایید.
عنوان انگلیسی
Psychopharmacological treatment of 2195 in-patients with borderline personality disorder: A comparison with other psychiatric disorders
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : European Neuropsychopharmacology, Volume 25, Issue 6, June 2015, Pages 763–772

کلمات کلیدی
اختلال شخصیت مرزی؛ داروهای روان گردان؛ داروهای تجویزی؛ ایمنی مواد مخدر؛ کواتیاپین؛ داروهای ضد افسردگی
پیش نمایش مقاله
پیش نمایش مقاله درمان روان دارو شناسی 2195 بیمار مبتلا به اختلال شخصیت مرزی: مقایسه با سایر اختلالات روانپزشکی

چکیده انگلیسی

Patients with borderline personality disorder (BPD) are usually prescribed a variety of psychotropic drugs; however, none is recommended in the guidelines nor has any been approved for this indication. As data on drug prescriptions for BPD are sparse, cross-sectional data from the European Drug Safety Project AMSP were used to analyse drug prescriptions of 2195 in-patients with BPD between 2001 and 2011, and the mean values, confidence intervals and regression analyses were calculated. 70% of all BPD patients were medicated with antipsychotics and/or antidepressants, 33% with anticonvulsants, 30% with benzodiazepines, and 4% with lithium; 90% received at least one, 80%≥2, and 54%≥3 psychotropic drugs concomitantly (mean: 2.8). Prescription rates for quetiapine, the single drug most often used in BPD (22%), increased significantly over time. In view of the high percentage of young females with BPD, 18–40 year-old female patients with BPD were compared with patients of the same age but with depression (unipolar and bipolar) and schizophrenia. Typical sedative antipsychotics and anticonvulsants were prescribed more often in BPD than in the other diagnostic groups, with the exception of bipolar depression; this was true for the single substances quetiapine, levomepromazine, chlorprothixene, carbamazepine, and valproate. A limitation of the study was the use of clinical data without verifying the diagnoses by structured interviews. Contrary to the guidelines, about 90% of in-patients with BPD received psychotropic drugs. Polypharmacy was common, and antipsychotics with sedative profiles such as quetiapine and mood-stabilizing anticonvulsants such as valproate appear to be preferred.

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