دانلود مقاله ISI انگلیسی شماره 69822
عنوان فارسی مقاله

اختلالات تشخیص چهره عاطفی و اثرات دارو در پیش آشکاری از طریق بیماری هانتینگتون مرحله دوم

کد مقاله سال انتشار مقاله انگلیسی ترجمه فارسی تعداد کلمات
69822 2013 9 صفحه PDF سفارش دهید محاسبه نشده
خرید مقاله
پس از پرداخت، فوراً می توانید مقاله را دانلود فرمایید.
عنوان انگلیسی
Emotional face recognition deficits and medication effects in pre-manifest through stage-II Huntington's disease
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Psychiatry Research, Volume 207, Issues 1–2, 15 May 2013, Pages 118–126

کلمات کلیدی
حالات چهره؛ چهره ها؛ نورولپتیک؛ سروتونین؛ عصبی
پیش نمایش مقاله
پیش نمایش مقاله اختلالات تشخیص چهره عاطفی و اثرات دارو در پیش آشکاری از طریق بیماری هانتینگتون مرحله دوم

چکیده انگلیسی

Facial emotion recognition impairments have been reported in Huntington's disease (HD). However, the nature of the impairments across the spectrum of HD remains unclear. We report on emotion recognition data from 344 participants comprising premanifest HD (PreHD) and early HD patients, and controls. In a test of recognition of facial emotions, we examined responses to six basic emotional expressions and neutral expressions. In addition, and within the early HD sample, we tested for differences on emotion recognition performance between those ‘on’ vs. ‘off’ neuroleptic or selective serotonin reuptake inhibitor (SSRI) medications. The PreHD groups showed significant (p<0.05) impaired recognition, compared to controls, on fearful, angry and surprised faces; whereas the early HD groups were significantly impaired across all emotions including neutral expressions. In early HD, neuroleptic use was associated with worse facial emotion recognition, whereas SSRI use was associated with better facial emotion recognition. The findings suggest that emotion recognition impairments exist across the HD spectrum, but are relatively more widespread in manifest HD than in the premanifest period. Commonly prescribed medications to treat HD-related symptoms also appear to affect emotion recognition. These findings have important implications for interpersonal communication and medication usage in HD.

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پس از پرداخت، فوراً می توانید مقاله را دانلود فرمایید.