دانلود مقاله ISI انگلیسی شماره 70953
عنوان فارسی مقاله

اختلال در تشخیص نشانه و بازیابی قصد زمینه اختلال حافظه آینده نگر در اسکیزوفرنی

کد مقاله سال انتشار مقاله انگلیسی ترجمه فارسی تعداد کلمات
70953 2007 7 صفحه PDF سفارش دهید محاسبه نشده
خرید مقاله
پس از پرداخت، فوراً می توانید مقاله را دانلود فرمایید.
عنوان انگلیسی
Deficits in cue detection and intention retrieval underlie prospective memory impairment in schizophrenia
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Schizophrenia Research, Volume 90, Issues 1–3, February 2007, Pages 344–350

کلمات کلیدی
اسکیزوفرنی؛ ارزیابی عصب روانشناختی؛ فرایندهای شناختی؛ حافظه اپیزودیک
پیش نمایش مقاله
پیش نمایش مقاله اختلال در تشخیص نشانه و بازیابی قصد زمینه اختلال حافظه آینده نگر در اسکیزوفرنی

چکیده انگلیسی

Emerging evidence indicates that individuals with schizophrenia (SCZ) may exhibit deficits in prospective memory (ProM), a dissociable and ecologically important aspect of episodic memory entailing the formation, maintenance, and execution of future intentions. The present study aimed to elucidate the component processes of ProM impairment in 41 individuals with SCZ relative to 41 demographically similar healthy comparison (HC) participants. Results revealed that the SCZ group performed worse than HCs on overall ProM, with comparable deficits on time- and event-based ProM trials. In the SCZ cohort, better ProM performance was associated with younger age and less severe negative symptoms. Although a significantly greater number of Task Substitution and Loss of Time errors were evident in the SCZ group as compared to HCs, the most prevalent error type in SCZ was characterized by a complete failure to respond to the ProM cue. Importantly, the SCZ and HC groups did not differ on a post-test multiple-choice recognition trial, suggesting adequate formation and maintenance (i.e., retention) of the ProM cue-intention pairing when self-directed monitoring and retrieval demands were minimized. Findings indicate that SCZ is associated with impairment in the cue detection and self-initiated retrieval components of executing future intentions, which is consistent with a possible prefrontostriatal loop neuropathogenesis. Further studies are needed to explore the neurobiological mechanisms of SCZ-associated ProM impairment and the impact of such deficits on daily functioning (e.g., medication compliance).

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پس از پرداخت، فوراً می توانید مقاله را دانلود فرمایید.