دانلود مقاله ISI انگلیسی شماره 71079
عنوان فارسی مقاله

افزایش سن و ارتباطات عصبی حافظه مبدا : سازماندهی مجدد کاربردی

کد مقاله سال انتشار مقاله انگلیسی ترجمه فارسی تعداد کلمات
71079 2012 -406 صفحه PDF سفارش دهید محاسبه نشده
خرید مقاله
پس از پرداخت، فوراً می توانید مقاله را دانلود فرمایید.
عنوان انگلیسی
Aging and the neural correlates of source memory: over-recruitment and functional reorganization
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Neurobiology of Aging, Volume 33, Issue 2, February 2012, Pages 425.e3–425.e18

کلمات کلیدی
پیری - حافظه زمینه - کنترل شناختی؛ fMRI؛ مدل سازی انتشار
پیش نمایش مقاله
پیش نمایش مقاله افزایش سن و ارتباطات عصبی حافظه مبدا : سازماندهی مجدد کاربردی

چکیده انگلیسی

Behavioral evidence suggests that memory for context (i.e., source memory) is more vulnerable to age-related decline than item memory. It is not clear, however, whether this pattern reflects a specific age-related deficit in context memory or a more general effect of task difficulty. In the present study, we used event-related functional magnetic resonance imaging (fMRI) with healthy younger and older adults to dissociate the effects of age, task (item vs. source memory), and task difficulty (1 vs. 2 study presentations) on patterns of blood oxygen level-dependent (BOLD) signal changes during memory retrieval. Behavioral performance was similar in both age groups, but was sensitive to task and difficulty (item > source; easy > difficult). Data-driven multivariate analyses revealed age differences consistent with age-related overrecruitment of frontoparietal regions during difficult task conditions, and age-related functional reorganization in bilateral frontal and right-lateralized posterior regions that were sensitive to difficulty in younger adults, but to task (i.e., context demand) in older adults. These findings support the hypothesis of a specific context memory deficit in older adults.

خرید مقاله
پس از پرداخت، فوراً می توانید مقاله را دانلود فرمایید.