دانلود مقاله ISI انگلیسی شماره 71256
عنوان فارسی مقاله

حافظه شناخت بویایی بلندمدت در افسردگی اساسی تک قطبی و بیماری آلزایمر

کد مقاله سال انتشار مقاله انگلیسی ترجمه فارسی تعداد کلمات
71256 2014 6 صفحه PDF سفارش دهید محاسبه نشده
خرید مقاله
پس از پرداخت، فوراً می توانید مقاله را دانلود فرمایید.
عنوان انگلیسی
Long-term odor recognition memory in unipolar major depression and Alzheimer׳s disease
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Psychiatry Research, Volume 220, Issue 3, 30 December 2014, Pages 861–866

کلمات کلیدی
بویایی؛ حافظه؛ بوی آشنا و ناآشنا - افسردگی؛ بیماری آلزایمر
پیش نمایش مقاله
پیش نمایش مقاله حافظه شناخت بویایی بلندمدت در افسردگی اساسی تک قطبی و بیماری آلزایمر

چکیده انگلیسی

Major depression and Alzheimer׳s disease (AD) are often observed in the elderly. The identification of specific markers for these diseases could improve their screening. The aim of this study was to investigate long-term odor recognition memory in depressed and AD patients, with a view to identifying olfactory markers of these diseases. We included 20 patients with unipolar major depressive episodes (MDE), 20 patients with mild to moderate AD and 24 healthy subjects. We investigated the cognitive profile and olfactory memory capacities (ability to recognize familiar and unfamiliar odors) of these subjects. Olfactory memory test results showed that AD and depressed patients were characterized by significantly less correct responses and more wrong responses than healthy controls. Detection index did not differ significantly between patients with major depression and those with AD when the results were analyzed for all odors. However, MDE patients displayed an impairment of olfactory memory for both familiar and unfamiliar odors, whereas AD subjects were impaired only in the recognition of unfamiliar odors, with respect to healthy subjects. If preservation of olfactory memory for familiar stimuli in patients with mild to moderate AD is confirmed, this test could be used in clinical practice as a complementary tool for diagnosis.

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