دانلود مقاله ISI انگلیسی شماره 71330
عنوان فارسی مقاله

عوارض پیری پیشرفته بر روی ارتباطات عصبی حافظه شناخت موفق

کد مقاله سال انتشار مقاله انگلیسی ترجمه فارسی تعداد کلمات
71330 2009 10 صفحه PDF سفارش دهید محاسبه نشده
خرید مقاله
پس از پرداخت، فوراً می توانید مقاله را دانلود فرمایید.
عنوان انگلیسی
Effects of advanced aging on the neural correlates of successful recognition memory
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Neuropsychologia, Volume 47, Issue 5, April 2009, Pages 1352–1361

کلمات کلیدی
بازیابی - fMRI؛ جبران خسارت؛ بیش از استخدام؛ حافظه اپیزودیک؛ قشر جداری میانی
پیش نمایش مقاله
پیش نمایش مقاله عوارض پیری پیشرفته بر روی ارتباطات عصبی حافظه شناخت موفق

چکیده انگلیسی

Functional neuroimaging studies have reported that the neural correlates of retrieval success (old > new effects) are larger and more widespread in older than in young adults. In the present study we investigated whether this pattern of age-related ‘over-recruitment’ continues into advanced age. Using functional magnetic resonance imaging (fMRI), retrieval-related activity from two groups (N = 18 per group) of older adults aged 84–96 years (‘old–old’) and 64–77 years (‘young–old’) was contrasted. Subjects studied a series of pictures, half of which were presented once, and half twice. At test, subjects indicated whether each presented picture was old or new. Recognition performance of the old–old subjects for twice-studied items was equivalent to that of the young–old subjects for once-studied items. Old > new effects common to the two groups were identified in several cortical regions, including medial and lateral parietal and prefrontal cortex. There were no regions where these effects were of greater magnitude in the old–old group, and thus no evidence of over-recruitment in this group relative to the young–old individuals. In one region of medial parietal cortex, effects were greater (and only significant) in the young–old group. The failure to find evidence of over-recruitment in the old–old subjects relative to the young–old group, despite their markedly poorer cognitive performance, suggests that age-related over-recruitment effects plateau in advanced age. The findings for the medial parietal cortex underscore the sensitivity of this cortical region to increasing age.

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