دانلود مقاله ISI انگلیسی شماره 71368
عنوان فارسی مقاله

افزایش آدرنرژیک تثبیت حافظه شناخت اشیا

کد مقاله سال انتشار مقاله انگلیسی ترجمه فارسی تعداد کلمات
71368 2007 6 صفحه PDF سفارش دهید محاسبه نشده
خرید مقاله
پس از پرداخت، فوراً می توانید مقاله را دانلود فرمایید.
عنوان انگلیسی
Adrenergic enhancement of consolidation of object recognition memory
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Neurobiology of Learning and Memory, Volume 88, Issue 1, July 2007, Pages 137–142

کلمات کلیدی
اپی نفرین - آدرنرژیک؛ حافظه شناخت - تثبیت حافظه
پیش نمایش مقاله
پیش نمایش مقاله افزایش آدرنرژیک تثبیت حافظه شناخت اشیا

چکیده انگلیسی

Extensive evidence indicates that epinephrine (EPI) modulates memory consolidation for emotionally arousing tasks in animals and human subjects. However, previous studies have not examined the effects of EPI on consolidation of recognition memory. Here we report that systemic administration of EPI enhances consolidation of memory for a novel object recognition (NOR) task under different training conditions. Control male rats given a systemic injection of saline (0.9% NaCl) immediately after NOR training showed significant memory retention when tested at 1.5 or 24, but not 96 h after training. In contrast, rats given a post-training injection of EPI showed significant retention of NOR at all delays. In a second experiment using a different training condition, rats treated with EPI, but not SAL-treated animals, showed significant NOR retention at both 1.5 and 24-h delays. We next showed that the EPI-induced enhancement of retention tested at 96 h after training was prevented by pretraining systemic administration of the β-adrenoceptor antagonist propranolol. The findings suggest that, as previously observed in experiments using aversively motivated tasks, epinephrine modulates consolidation of recognition memory and that the effects require activation of β-adrenoceptors.

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