دانلود مقاله ISI انگلیسی شماره 71420
عنوان فارسی مقاله

اثر سالمندی بر روی فعالیت رمزگذاری حافظه موفق گذرا و پایدار

کد مقاله سال انتشار مقاله انگلیسی ترجمه فارسی تعداد کلمات
71420 2007 10 صفحه PDF سفارش دهید 6772 کلمه
خرید مقاله
پس از پرداخت، فوراً می توانید مقاله را دانلود فرمایید.
عنوان انگلیسی
Effects of aging on transient and sustained successful memory encoding activity
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Neurobiology of Aging, Volume 28, Issue 11, November 2007, Pages 1749–1758

کلمات کلیدی
پیری - تجزیه و تحلیل ترکیبی؛ حافظه پس از آن؛ رمزگذاری - fMRI
پیش نمایش مقاله
پیش نمایش مقاله اثر سالمندی بر روی فعالیت رمزگذاری حافظه موفق گذرا و پایدار

چکیده انگلیسی

Event-related fMRI studies have investigated age-related changes in encoding by identifying greater activity for items that are later remembered than for those that are forgotten (difference in memory, or Dm). The present study used hybrid blocked/event-related analyses to distinguish between transient Dm versus sustained Dm. Dm was identified as parametric increases in encoding activity as a function of a combined subsequent memory/confidence scale. Dm was measured in each trial (transient activity) and in blocks of eight trials (sustained activity). Transient Dm analyses showed age-related reductions in the left hippocampus but increases in left prefrontal cortex (PFC). Sustained Dm analyses showed age-related reductions in right PFC, but no region showing increased activity in older adults. These findings suggests that during semantic classification older adults show less spontaneous hippocampal-mediated encoding processes, but greater PFC-mediated semantic processes. Additionally, the decline in sustained Dm in PFC may involve age-related deficits in sustained attention that impact encoding processes. The results underscore the importance of investigating aging effects on both transient and sustained neural activity.

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