دانلود مقاله ISI انگلیسی شماره 71556
عنوان فارسی مقاله

تثبیت حافظه آفلاین دچار اختلال شده در افسردگی

کد مقاله سال انتشار مقاله انگلیسی ترجمه فارسی تعداد کلمات
71556 2010 9 صفحه PDF سفارش دهید محاسبه نشده
خرید مقاله
پس از پرداخت، فوراً می توانید مقاله را دانلود فرمایید.
عنوان انگلیسی
Impaired off-line memory consolidation in depression
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : European Neuropsychopharmacology, Volume 20, Issue 8, August 2010, Pages 553–561

کلمات کلیدی
افسردگی؛ خواب؛ حافظه
پیش نمایش مقاله
پیش نمایش مقاله تثبیت حافظه آفلاین دچار اختلال شده در افسردگی

چکیده انگلیسی

50 medicated patients with an acute episode of MD, 50 normal controls and 12 patients with a remitted episode of MD were assessed using a sequential finger tapping task before and after a night of sleep. Although depressed patients and control subjects did not differ in practice-dependent learning, healthy subjects showed markedly overnight improvements in tapping performance of 18% while patients failed to show any improvement. This pattern became even more striking when the subjects were divided by an age threshold of 30 years: In the 30+ yrs group the healthy subjects showed 16% overnight increase in motor performance, whereas the patients showed − 10% overnight decrease. In contrast, patients and controls in the ≤ 30 yrs group showed virtually the same motor performance, as well as remitted patients and controls in the 30+ yrs group. In addition, the younger controls showed stronger overnight improvements than the older controls. This pattern might be interpreted as a synergistic interaction between age and depression: Off-line motor memory consolidation is not affected in young patients, but severely impaired in older patients with an acute episode of MD. This impairment seems to recover after remission from depression.

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