دانلود مقاله ISI انگلیسی شماره 71558
عنوان فارسی مقاله

استرس و حافظه: مخالفت با اثرات گلوکوکورتیکوئیدها بر تثبیت حافظه و فراخوانی حافظه

کد مقاله سال انتشار مقاله انگلیسی ترجمه فارسی تعداد کلمات
71558 2002 18 صفحه PDF سفارش دهید محاسبه نشده
خرید مقاله
پس از پرداخت، فوراً می توانید مقاله را دانلود فرمایید.
عنوان انگلیسی
Stress and Memory: Opposing Effects of Glucocorticoids on Memory Consolidation and Memory Retrieval ☆☆☆
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Neurobiology of Learning and Memory, Volume 78, Issue 3, November 2002, Pages 578–595

کلمات کلیدی
آمیگدال؛ کورتیکوسترون؛ دگزامتازون؛ انگیختگی عاطفی؛ هیپوکامپ؛ ذخیره سازی حافظه؛ نوراپی نفرین
پیش نمایش مقاله
پیش نمایش مقاله استرس و حافظه: مخالفت با اثرات گلوکوکورتیکوئیدها بر تثبیت حافظه و فراخوانی حافظه

چکیده انگلیسی

It is well established that glucocorticoid hormones, secreted by the adrenal cortex after a stressful event, influence cognitive performance. Some studies have found glucocorticoid-induced memory enhancement. However, many studies have reported impairing effects of glucocorticoids on memory function. This paper reviews recent findings from this laboratory on the acute effects of glucocorticoids in rats on specific memory phases, i.e., memory consolidation and memory retrieval. The evidence suggests that the consequences of glucocorticoid activation on cognition depend largely on the different memory phases investigated. Posttraining activation of glucocorticoid-sensitive pathways involving glucocorticoid receptors enhances memory consolidation in a pattern highly similar to that previously described for adrenal catecholamines. Also, similar to catecholamine effects on memory consolidation, glucocorticoid influences on memory consolidation depend on noradrenergic activation of the basolateral complex of the amygdala and interactions with other brain regions. By contrast, memory retrieval processes are usually impaired with high circulating levels of glucocorticoids or following infusions of glucocorticoid receptor agonists into the hippocampus. The hypothesis is proposed that these apparently dual effects of glucocorticoids on memory consolidation and memory retrieval might be related and that the basolateral complex of the amygdala is a key structure in a memory-modulatory system that regulates, in concert with other brain regions, stress and glucocorticoid effects on both memory consolidation and memory retrieval.

خرید مقاله
پس از پرداخت، فوراً می توانید مقاله را دانلود فرمایید.