دانلود مقاله ISI انگلیسی شماره 71905
عنوان فارسی مقاله

حافظه شرح حال در افسردگی: مطالعه fMRI

کد مقاله سال انتشار مقاله انگلیسی ترجمه فارسی تعداد کلمات
71905 2012 9 صفحه PDF سفارش دهید محاسبه نشده
خرید مقاله
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عنوان انگلیسی
Autobiographical memory in depression: An fMRI study
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Psychiatry Research: Neuroimaging, Volume 201, Issue 2, 28 February 2012, Pages 98–106

کلمات کلیدی
افسردگی؛ حافظه شرح حال؛ fMRI؛ تصویربرداری عصبی
پیش نمایش مقاله
پیش نمایش مقاله حافظه شرح حال در افسردگی: مطالعه fMRI

چکیده انگلیسی

Depression is associated with three distinct alterations in memory functioning: mood-congruent recall, overgenerality, and intrusive memories. These concern the autobiographical memory system, yet no previous studies have examined the neural correlates of autobiographical memory function in depression. In the present study we used functional magnetic resonance imaging (fMRI) to assess depressed and control participants during an autobiographical memory task. In their first visit to the laboratory, participants wrote a narrative account of a distressing event. Participants were scanned during the second visit while they viewed old items from their narrative and new words or phrases in a recognition memory task. Activity common to both groups during the successful identification of personal emotional memories was observed in regions previously associated with autobiographical memory retrieval. Reduced activity in the depressed group was observed in three regions of the prefrontal cortex associated with cognitive, emotional, and memory inhibition. These results are consistent with a failure by depressed individuals to inhibit task-irrelevant information during an autobiographical memory task.

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