دانلود مقاله ISI انگلیسی شماره 72678
عنوان فارسی مقاله

اختلال در نظم مهار حرکت تصویری در افسردگی اساسی

کد مقاله سال انتشار مقاله انگلیسی ترجمه فارسی تعداد کلمات
72678 2016 8 صفحه PDF سفارش دهید محاسبه نشده
خرید مقاله
پس از پرداخت، فوراً می توانید مقاله را دانلود فرمایید.
عنوان انگلیسی
Dysregulation of visual motion inhibition in major depression
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Psychiatry Research, Volume 240, 30 June 2016, Pages 214–221

کلمات کلیدی
شناختی؛ علوم اعصاب - حرکت؛ چشم انداز؛ فراگیر مرکز؛ افسردگی؛ روان؛ حالت
پیش نمایش مقاله
پیش نمایش مقاله اختلال در نظم مهار حرکت تصویری در افسردگی اساسی

چکیده انگلیسی

Individuals with depression show depleted concentrations of the inhibitory neurotransmitter GABA in occipital (visual) cortex, predicting weakened inhibition within their visual systems. Yet, visual inhibition in depression remains largely unexplored. To fill this gap, we examined the inhibitory process of center-surround suppression (CSS) of visual motion in depressed individuals. Perceptual performance in discriminating the direction of motion was measured as a function of stimulus presentation time and contrast in depressed individuals (n=27) and controls (n=22). CSS was operationalized as the accuracy difference between conditions using large (7.5°) and small (1.5°) grating stimuli. Both depressed and control participants displayed the expected advantage in accuracy for small stimuli at high contrast. A significant interaction emerged between subject group, contrast level and presentation time, indicating that alterations of CSS in depression were modulated by stimulus conditions. At high contrast, depressed individuals showed significantly greater CSS than controls at the 66 ms presentation time (where the effect peaked in both groups). The results' specificity and dependence on stimulus features such as contrast, size and presentation time suggest that they arise from changes in early visual processing, and are not the results of a generalized deficit or cognitive bias.

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