دانلود مقاله ISI انگلیسی شماره 72683
عنوان فارسی مقاله

شناخت به عنوان یک هدف در افسردگی اساسی: تحولات جدید

کد مقاله سال انتشار مقاله انگلیسی ترجمه فارسی تعداد کلمات
72683 2015 17 صفحه PDF سفارش دهید محاسبه نشده
خرید مقاله
پس از پرداخت، فوراً می توانید مقاله را دانلود فرمایید.
عنوان انگلیسی
Cognition as a target in major depression: New developments
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : European Neuropsychopharmacology, Volume 25, Issue 2, February 2015, Pages 231–247

کلمات کلیدی
شناخت؛ افسردگی شدید؛ تک درمانی؛ درمان کمکی
پیش نمایش مقاله
پیش نمایش مقاله شناخت به عنوان یک هدف در افسردگی اساسی: تحولات جدید

چکیده انگلیسی

Major depressive disorder (MDD) is a highly prevalent and disabling psychiatric illness often accompanied of cognitive dysfunction which may persist even when patients achieve clinical remission. Currently, cognitive deficits emerge as a potential target because they compromise the functional outcome of depressed patients. The aim of this study was to review data for several potential pharmacological treatments targeting cognition in MDD, resulting from monotherapy or adjunctive treatment. An extensive and systematic Pubmed/Medline search of the published literature until March 2014 was conducted using a variety of search term to find relevant articles. Bibliographies of retrieved papers were further examined for publications of interest. Searches were limited to articles available in English language. We describe studies using modafinil, lisdexamfetamine, ketamine, lanicemine, memantine, galantamine, donepezil, vortioxetine, intranasal oxytocin, omega-3, s-adenosyl-methionine, scopolamine and erythropoietin. From these articles, we determined that there are a number of promising new therapies, pharmacological agents or complementary medicines, but data are just emerging. Drugs and therapies targeting cognitive dysfunction in MDD should prove effective in improving specific cognitive domains and functioning, while ruling out pseudospecificity.

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پس از پرداخت، فوراً می توانید مقاله را دانلود فرمایید.