دانلود مقاله ISI انگلیسی شماره 72814
عنوان فارسی مقاله

اساس عصبی عملکرد بویایی و ارتباط آن با فقدان لذت در افراد مبتلا به اسکیزوتایپی: مطالعه اکتشافی

کد مقاله سال انتشار مقاله انگلیسی ترجمه فارسی تعداد کلمات
72814 2015 6 صفحه PDF سفارش دهید محاسبه نشده
خرید مقاله
پس از پرداخت، فوراً می توانید مقاله را دانلود فرمایید.
عنوان انگلیسی
The neural basis of olfactory function and its relationship with anhedonia in individuals with schizotypy: An exploratory study
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Psychiatry Research: Neuroimaging, Volume 234, Issue 2, 30 November 2015, Pages 202–207

کلمات کلیدی
بویایی؛ فقدان لذت؛ اسکیزوتایپی؛ تصویربرداری
پیش نمایش مقاله
پیش نمایش مقاله اساس عصبی عملکرد بویایی و ارتباط آن با فقدان لذت در افراد مبتلا به اسکیزوتایپی: مطالعه اکتشافی

چکیده انگلیسی

Previous studies have established a linkage between olfactory deficits and negative symptoms in schizophrenia. However, it is not known whether olfactory function is associated with hedonic traits in individuals with schizotypy. Seventeen individuals with schizotypy and 18 age- and sex-matched controls participated in this study. Hedonic traits were assessed with the Chapman Scales for Physical and Social Anhedonia (CSAS and CPAS). Olfactory function was assessed with the Sniffin' Stick Test (olfactory threshold, odour discrimination and odour identification). All participants undertook a structural imaging scan for grey matter volume measurements. Individuals with schizotypy had significantly higher CSAS and CPAS scores than healthy controls. They had normal olfactory function. Their odour identification ability was inversely correlated with physical and social anhedonia. The volume of the right parahippocampal gyrus was positively associated with odour identification ability, and negatively associated with physical and social anhedonia. Furthermore, mediation analysis suggested that odour identification ability influences anhedonia through its effect on the right parahippocampal gyrus. No such relationship was found in controls. These findings suggest that there is a relationship between odour identification and anhedonia in individuals with schizotypy, and the association may be mediated by parahippocampal gyrus volume.

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