دانلود مقاله ISI انگلیسی شماره 73182
عنوان فارسی مقاله

وابستگی به کوکائین و پارانویا ناشی از کوکائین و پاسخ شنوایی تاخیردار و دروازه حسی برانگیخته

کد مقاله سال انتشار مقاله انگلیسی ترجمه فارسی تعداد کلمات
73182 2006 8 صفحه PDF سفارش دهید محاسبه نشده
خرید مقاله
پس از پرداخت، فوراً می توانید مقاله را دانلود فرمایید.
عنوان انگلیسی
Cocaine-dependence and cocaine-induced paranoia and mid-latency auditory evoked responses and sensory gating ☆
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Psychiatry Research, Volume 145, Issues 2–3, 7 December 2006, Pages 147–154

کلمات کلیدی
پتانسیلهای برانگیخته - اواسط زمان تاخیر
پیش نمایش مقاله
پیش نمایش مقاله وابستگی به کوکائین و پارانویا ناشی از کوکائین و پاسخ شنوایی تاخیردار و دروازه حسی برانگیخته

چکیده انگلیسی

Cocaine-dependence has been shown to affect the amplitudes of the P50 mid-latency auditory evoked response (MLAER) as well as P50 sensory gating. The effects on subsequent MLAERs (N100 and P200) have not been examined. The objective of the current study was to further assess the effects of chronic cocaine use on the P50, N100, and P200 components. Thirty-four, at least three weeks abstinent, cocaine-dependent individuals and 34 age and gender matched healthy controls were examined. The amplitudes, latencies and gating measures were calculated and compared between the groups. The N100 and P200 were significantly smaller in patients as compared to control subjects. Sensory gating of the P50, the N100, and the P200 were deficient in cocaine-dependent subjects. Latencies of all measured components were prolonged in subjects who reported developing paranoia while intoxicated. Finally, a positive correlation was found between length of abstinence and evoked response amplitudes. We conclude that the effects of cocaine on sensory gating extend beyond the P50 to the N100 and the P200 components. The data also suggest that prolonged latency of the evoked potentials may be a correlate of cocaine-induced psychosis. Finally, the data suggest that some recovery of amplitude and gating occurs with abstinence.

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