دانلود مقاله ISI انگلیسی شماره 73996
عنوان فارسی مقاله

خط سیر طولی رفتارهای ناهنجار در سندرم ایکس شکننده

کد مقاله سال انتشار مقاله انگلیسی ترجمه فارسی تعداد کلمات
73996 2014 11 صفحه PDF سفارش دهید 6380 کلمه
خرید مقاله
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عنوان انگلیسی
Longitudinal trajectories of aberrant behavior in fragile X syndrome
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Research in Developmental Disabilities, Volume 35, Issue 11, November 2014, Pages 2691–2701

کلمات کلیدی
سندرم ایکس شکننده؛ رفتارهای ناهنجار؛ داده های طولی - رفتار سازشی
پیش نمایش مقاله
پیش نمایش مقاله خط سیر طولی رفتارهای ناهنجار در سندرم ایکس شکننده

چکیده انگلیسی

The Aberrant Behavior Checklist-Community (ABC-C; Aman et al., 1995) has been increasingly adopted as a primary tool for measuring behavioral change in clinical trials for individuals with fragile X syndrome (FXS). To our knowledge, however, no study has documented the longitudinal trajectory of aberrant behaviors in individuals with FXS using the ABC-C. As part of a larger longitudinal study, we examined scores obtained on the ABC-C subscales for 124 children and adolescents (64 males, 60 females) with FXS who had two or more assessments (average interval between assessments was approximately 4 years). Concomitant changes in age-equivalent scores on the Vineland Adaptive Behavior Scales (VABS) were also examined. As expected for an X-linked genetic disorder, males with FXS obtained significantly higher scores on all subscales of the ABC-C and significantly lower age-equivalent scores on the VABS than females with FXS. In both males and females with FXS, scores on the Irritability/Agitation and Hyperactivity/Noncompliance subscales of the ABC-C decreased significantly with age, with little to no change occurring over time on the Lethargy/Social Withdrawal, Stereotypic Behavior, and Inappropriate Speech subscales. The decrease in scores on the Hyperactivity/Noncompliance domain was significantly greater for males than for females. In both males and females, age-equivalent scores on the VABS increased significantly over this developmental period. These results establish a basis upon which to evaluate long-term outcomes from intervention-based research. However, longitudinal direct observational studies are needed to establish whether the severity of problem behavior actually decreases over time in this population.

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