دانلود مقاله ISI انگلیسی شماره 75470
عنوان فارسی مقاله

نور درمانی در درمان بیماران مبتلا به افسردگی دو قطبی: مطالعه فراتحلیلی

کد مقاله سال انتشار مقاله انگلیسی ترجمه فارسی تعداد کلمات
75470 2016 11 صفحه PDF سفارش دهید محاسبه نشده
خرید مقاله
پس از پرداخت، فوراً می توانید مقاله را دانلود فرمایید.
عنوان انگلیسی
Light therapy in the treatment of patients with bipolar depression: A meta-analytic study
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : European Neuropsychopharmacology, Volume 26, Issue 6, June 2016, Pages 1037–1047

کلمات کلیدی
اختلال دو قطبی؛ نور درمانی؛ فراتحلیل؛
پیش نمایش مقاله
پیش نمایش مقاله نور درمانی در درمان بیماران مبتلا به افسردگی دو قطبی: مطالعه فراتحلیلی

چکیده انگلیسی

Light therapy (LT) has been widely used in the treatment of seasonal affective disorder. Recently some evidence indicated that LT may play a role in bipolar depression, either as monotherapy or in combination with total sleep deprivation (TSD). However, the studies examining the treatment effect of LT in bipolar depression resulted in inconsistent findings. To clarify the role of LT in the disorder, we conducted a meta-analysis to compare the efficacy of LT in the treatment of bipolar depression. The results of individual studies were synthesized by a random effects model. Nine studies including 489 patients with bipolar depression were included in this current meta-analysis. We found that disease severity was significantly decreased after LT, in both with and without TSD, and with concomitant medication (p<0.001). Augmentation treatment with LT significantly decreased disease severity compared to treatment without LT (p=0.024). Our results highlight the significant efficacy of LT, either as monotherapy or in combination with TSD, in the treatment of bipolar depression. However, the detailed mechanism of LT still remains elusive. Further well-designed controlled trials are required to investigate the optimal intensity and frequency of LT in the treatment of bipolar depression.

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