دانلود مقاله ISI انگلیسی شماره 75516
عنوان فارسی مقاله

تجلیات الکتروفیزیولوژیک از ارزیابی محرک، بازداری پاسخ و پردازش حرکتی در بیماران سندرم تورت

کد مقاله سال انتشار مقاله انگلیسی ترجمه فارسی تعداد کلمات
75516 2009 19 صفحه PDF سفارش دهید محاسبه نشده
خرید مقاله
پس از پرداخت، فوراً می توانید مقاله را دانلود فرمایید.
عنوان انگلیسی
Electrophysiological manifestations of stimulus evaluation, response inhibition and motor processing in Tourette syndrome patients
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Psychiatry Research, Volume 167, Issue 3, 30 May 2009, Pages 202–220

کلمات کلیدی
سازگاری محرک و پاسخ؛ بازداری؛ آماده سازی حرکتی ؛ کار استروپ؛ قشر پیش حرکتی
پیش نمایش مقاله
پیش نمایش مقاله تجلیات الکتروفیزیولوژیک از ارزیابی محرک، بازداری پاسخ و پردازش حرکتی در بیماران سندرم تورت

چکیده انگلیسی

Gilles de la Tourette syndrome (GTS) is a neuropsychiatric disorder with childhood onset presenting with multiple fluctuating motor tics and one or more phonic tics. A significant proportion of people suffering from GTS are still symptomatic in adulthood and present other emotional and cognitive difficulties, along with motor problems that often accompany these comorbid conditions. The nature of these difficulties is still poorly understood and multiple comorbidities are often inadequately controlled. The current study investigates both stimulus evaluation and motor processing in GTS while controlling for comorbidity. Fifteen adults with GTS and 20 control participants were matched on gender, laterality and intelligence. The P300 component, the no-go anteriorization (NGA) as well as the stimulus and response-locked lateralized-readiness potentials (S-LRP, R-LRP) were elicited during a stimulus–response compatibility (SRC) paradigm. The standard version of the Stroop Color–Word Test (SCWT) was also administered. Reaction times showed that participants with GTS processed both the SRC and the SCWT more rapidly than the control group, while producing a delayed P300 peak latency. The GTS group also showed faster S-LRP onset in response to the incompatible and faster processing of interference in the SCWT. There was also a tendency toward a greater frontal shift of the NGA in the GTS group. The P300 latency showed that with GTS patients, stimulus evaluation occurs later whereas the overlapping pre-motor response selection processes occur faster. Our findings are congruent with a probable cortical motor over-activation hypothesis of GTS involving faster motor program selection in processing conflicting SR configuration.

خرید مقاله
پس از پرداخت، فوراً می توانید مقاله را دانلود فرمایید.