دانلود مقاله ISI انگلیسی شماره 78270
عنوان فارسی مقاله

یک دوز از اسپری اکسی توسین بینی شناخت اجتماعی مرتبه بالاتر در اسکیزوفرنی را بهبود می بخشد

کد مقاله سال انتشار مقاله انگلیسی ترجمه فارسی تعداد کلمات
78270 2015 6 صفحه PDF سفارش دهید محاسبه نشده
خرید مقاله
پس از پرداخت، فوراً می توانید مقاله را دانلود فرمایید.
عنوان انگلیسی
A single dose of oxytocin nasal spray improves higher-order social cognition in schizophrenia
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Schizophrenia Research, Volume 168, Issue 3, November 2015, Pages 628–633

کلمات کلیدی
نوروپپتید؛ تشخیص احساسات؛ رفتار اجتماعی؛ روان پریشی؛ هورمون
پیش نمایش مقاله
پیش نمایش مقاله یک دوز از اسپری اکسی توسین بینی شناخت اجتماعی مرتبه بالاتر در اسکیزوفرنی را بهبود می بخشد

چکیده انگلیسی

Schizophrenia is associated with significant impairments in both higher and lower order social cognitive performance and these impairments contribute to poor social functioning. People with schizophrenia report poor social functioning to be one of their greatest unmet treatment needs. Recent studies have suggested the potential of oxytocin as such a treatment, but mixed results render it uncertain what aspects of social cognition are improved by oxytocin and, subsequently, how oxytocin might best be applied as a therapeutic. The aim of this study was to determine whether a single dose of oxytocin improved higher-order and lower-order social cognition performance for patients with schizophrenia across a well-established battery of social cognition tests. Twenty-one male patients received both a single dose of oxytocin nasal spray (24 IU) and a placebo, two weeks apart in a randomized within-subjects placebo controlled design. Following each administration, participants completed the social cognition tasks, as well as a test of general neurocognition. Results revealed that oxytocin particularly enhanced performance on higher order social cognition tasks, with no effects on general neurocognition. Results for individual tasks showed most improvement on tests measuring appreciation of indirect hints and recognition of social faux pas. These results suggest that oxytocin, if combined to enhance social cognition learning, may be beneficial when targeted at higher order social cognition domains. This study also suggests that these higher order tasks, which assess social cognitive processing in a social communication context, may provide useful markers of response to oxytocin in schizophrenia.

خرید مقاله
پس از پرداخت، فوراً می توانید مقاله را دانلود فرمایید.