Abstract
Although a substantial body of literature has established a relationship between cue reactivity and theoretically relevant addiction variables, the association with treatment process variables remains largely unexplored. In the current investigation, 62 smokers participated in a smoking cue reactivity study, and subsequently enrolled in a smoking cessation program. Hierarchical regressions revealed mean heart rate during the cue presentation phase of the laboratory-based assessment predicted final session smoking rate and expired CO level. Fagerström Tolerance Questionnaire score also predicted final session smoking rate. To the extent that rate reduction serves as an index of treatment progress, it may be of value in future cue reactivity research.
. Results
2.1. Participant characteristics
Table 1 presents characteristics for the study sample. Overall, participants were predominantly high-school educated, middle-aged males who were chronic, nicotine dependent smokers.
Table 1.
Participant characteristics
Mean SD
Daily rate 29.51 13.09
Years smoking 29.64 12.75
FTQ score 6.61 1.76
Age 49.03 12.09
Education 13.31 3.06
Race (African American) 34%
Table options
2.2. Pretreatment analyses
Pretreatment Smoking Rate was predicted by FTQ score, Fchange = 27.61, p < .001. Desire to Smoke rating was also related, Fchange = 5.72, p < .02. All other variables were non-significant. Pretreatment CO level was unrelated to all predictors (the overall IBI analysis was significant, but all individual variables failed to enter into the final equation) ( Table 2).
Table 2.
Final hierarchical regression models for pretreatment variables
1. Pretreatment smoking rate
Variable β-in R2 Ch F Ch p
a. IBI measurements: adjusted R2 = .204; F(5,97) = 6.243, p < .001
Deprivation ns
FTQ .463 .202 25.879 .000
BL IBI ns
CP IBI ns
b. Desire ratings: adjusted R2 = .257; F(5,100) = 8.254, p < .001
Deprivation ns
FTQ .468 .207 27.613 .000
BL desire rating .237 .041 5.724 .019
CP desire rating ns
c. Other self-report ratings: adjusted R2 = .188; F(9,83) = 3.371, p < .005
Deprivation ns
FTQ .456 .193 22.286 .000
BL other ratings ns
CP other ratings ns
2. Pretreatment expired CO level
a. IBI measurements: adjusted R2 = .085; F(5,96) = 2.885, p < .02 (all blocks ns)
b. Desire rating: F(5,99) = 1.700, p = .142 (ns)
c. Other self-report ratings: F(9,83) = 1.254, p = .275 (ns)
FTQ = Fagerström Tolerance Questionnaire; BL = Baseline Phase; CP = Cue Presentation Phase.
Table options
2.3. End-of-treatment analyses
End-of-Treatment Smoking Rate was predicted by FTQ score, Fchange = 6.29, p < .02. Smoking Rate was also predicted by Cue Presentation phase IBI, Fchange = 4.16, p < .05, such that shorter IBI (i.e., higher heart rate response) predicted greater Smoking Rate. In a similar fashion, shorter IBI during the Cue Presentation phase predicted higher CO level at Session 6, Fchange = 6.11, p < .02. No other findings emerged ( Table 3).
Table 3.
Final hierarchical regression models for end-of-treatment variables
1. End-of-treatment smoking rate
Variable β-in R2 Ch F Ch p
a. IBI measurements: adjusted R2 = .171; F(5,57) = 3.561, p < .01
Deprivation ns
FTQ .305 .202 6.289 .015
BL IBI ns
CP IBI − .636 .056 4.163 .046
b. Desire rating: adjusted R2 = .184; F(5,59) = 3.893, p < .005
Deprivation ns
FTQ .345 .111 8.267 .006
BL desire rating ns
CP desire rating ns
c. Other self-report ratings: adjusted R2 = .163; F(9,50) = 2.278, p < .04
Deprivation ns
FTQ .374 .126 8.791 .004
BL other ratings ns
CP other ratings ns
2. End-of-treatment expired CO level
a. IBI measurements: adjusted R2 = .100; F(5,57) = 2.382, p < .05
Deprivation ns
FTQ ns
BL IBI ns
CP IBI − .802 .089 6.105 .016
b. Desire rating: F(5,59) = 1.666, p = .157 (ns)
c. Other self-report ratings: F(9,50) = 0.862, p = .565 (ns)
FTQ = Fagerström Tolerance Questionnaire; BL = Baseline Phase; CP = Cue Presentation Phase.