دانلود مقاله ISI انگلیسی شماره 126910
ترجمه فارسی عنوان مقاله

مشارکت گریرس غده وسط در تغییر زبان به عنوان نشان داده شده توسط نقشه برداری الکترومغناطیسی و تصویربرداری رزونانس مغناطیسی عملکردی در بیماران تومور دو زبانه

عنوان انگلیسی
Involvement of the middle frontal gyrus in language switching as revealed by electrical stimulation mapping and functional magnetic resonance imaging in bilingual brain tumor patients
کد مقاله سال انتشار تعداد صفحات مقاله انگلیسی
126910 2018 15 صفحه PDF
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Cortex, Volume 99, February 2018, Pages 78-92

پیش نمایش مقاله
پیش نمایش مقاله  مشارکت گریرس غده وسط در تغییر زبان به عنوان نشان داده شده توسط نقشه برداری الکترومغناطیسی و تصویربرداری رزونانس مغناطیسی عملکردی در بیماران تومور دو زبانه

چکیده انگلیسی

Language functional maps were reconstructed on the basis of the intraoperative electrical stimulation results and compared to the functional magnetic resonance findings. Single language-naming sites (Spanish and Catalan), as well as language switching naming sites were detected by electrical stimulation mapping in 8 patients (in one patient only Spanish related sites were detected). Single naming points outnumbered the switching points and did not overlap with each other. Within the frontal lobe, the single language naming sites were found significantly more frequently within the inferior frontal gyrus as compared to the middle frontal gyrus [X2 (1) = 20.3, p < .001]. Contrarily, switching naming sites were distributed across the middle frontal gyrus significantly more often than within the inferior frontal gyrus [X2 (1) = 4.1, p = .043]. Notably, there was not always an overlap between functional magnetic resonance and electrical stimulation mapping findings. After surgery, patients did not report involuntary language switching and their neuropsychological scores did not differ significantly from the pre-surgical examinations. Our results suggest a functional division of the frontal cortex between naming and language switching functions, supporting that non-language specific cognitive control prefrontal regions (middle frontal gyrus) are essential to maintain an effective communication together with the classical language-related sites (inferior frontal gyrus).