دانلود مقاله ISI انگلیسی شماره 71125
ترجمه فارسی عنوان مقاله

اجرایی بزرگ و اختلال در عملکرد حافظه بصری در اختلال دو قطبی و اختلالات مصرف مواد

عنوان انگلیسی
Greater executive and visual memory dysfunction in comorbid bipolar disorder and substance use disorder
کد مقاله سال انتشار تعداد صفحات مقاله انگلیسی
71125 2012 6 صفحه PDF
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Psychiatry Research, Volume 200, Issues 2–3, 30 December 2012, Pages 252–257

ترجمه کلمات کلیدی
اختلالات خلقی؛ الکل؛ تشخیص دوگانه؛ شناختی؛ نوروسایکولوژی
کلمات کلیدی انگلیسی
Mood disorders; Alcohol; Dual diagnosis; Cognition; Neuropsychology
پیش نمایش مقاله
پیش نمایش مقاله  اجرایی بزرگ و اختلال در عملکرد حافظه بصری در اختلال دو قطبی و اختلالات مصرف مواد

چکیده انگلیسی

Measures of cognitive dysfunction in Bipolar Disorder (BD) have identified state and trait dependent metrics. An influence of substance abuse (SUD) on BD has been suggested. This study investigates potential differential, additive, or interactive cognitive dysfunction in bipolar patients with or without a history of SUD. Two hundred fifty-six individuals with BD, 98 without SUD and 158 with SUD, and 97 Healthy Controls (HC) completed diagnostic interviews, neuropsychological testing, and symptom severity scales. The BD groups exhibited poorer performance than the HC group on most cognitive factors. The BD with SUD exhibited significantly poorer performance than BD without SUD in visual memory and conceptual reasoning/set-shifting. In addition, a significant interaction effect between substance use and depressive symptoms was found for auditory memory and emotion processing. BD patients with a history of SUD demonstrated worse visual memory and conceptual reasoning skills above and beyond the dysfunction observed in these domains among individuals with BD without SUD, suggesting greater impact on integrative, gestalt-driven processing domains. Future research might address longitudinal outcome as a function of BD, SUD, and combined BD/SUD to evaluate neural systems involved in risk for, and effects of, these illnesses.