To allow the dual-fuel operation over the whole engine map without exceeding the mechanical limitations of the engine, an optimized dual-fuel combustion strategy is proposed in this research. The combustion strategy changes as the engine load increases, starting from a fully premixed reactivity controlled compression ignition combustion up to around 8 bar IMEP, then switching to a highly premixed reactivity controlled compression ignition combustion up to 15 bar IMEP, and finally moving to a mainly diffusive dual-fuel combustion to reach the full load operation. The engine mapping results obtained using this combustion strategy show that reactivity controlled compression ignition combustion allows fulfilling the EURO VI NOx limit up to 14 bar IMEP. Ultra-low soot emissions are also achieved when the fully premixed combustion is promoted, however, the soot levels rise notably as the combustion strategy moves to a less premixed pattern. Finally, the direct comparison of reactivity controlled compression ignition versus conventional diesel combustion using the nominal engine settings, reveals that reactivity controlled compression ignition can be a potential solution to reduce the selective catalyst reduction and diesel particulate filter aftertreatment necessities with a simultaneous improving of the thermal efficiency.