دانلود مقاله ISI انگلیسی شماره 39756
ترجمه فارسی عنوان مقاله

ادراکپریشی شنوایی غیرکلامی با ضایعه در قسمت Wernicke

عنوان انگلیسی
Nonverbal auditory agnosia with lesion to Wernicke's area
کد مقاله سال انتشار تعداد صفحات مقاله انگلیسی
39756 2010 7 صفحه PDF
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Neuropsychologia, Volume 48, Issue 1, January 2010, Pages 107–113

ترجمه کلمات کلیدی
صداهای زیست محیطی - قشر تمپورال - آفازی - تفکیک - fMRI
کلمات کلیدی انگلیسی
Environmental sounds; Temporal cortex; Aphasia; Dissociation; fMRI
پیش نمایش مقاله
پیش نمایش مقاله  ادراکپریشی شنوایی غیرکلامی با ضایعه در قسمت Wernicke

چکیده انگلیسی

We report the case of patient M, who suffered unilateral left posterior temporal and parietal damage, brain regions typically associated with language processing. Language function largely recovered since the infarct, with no measurable speech comprehension impairments. However, the patient exhibited a severe impairment in nonverbal auditory comprehension. We carried out extensive audiological and behavioral testing in order to characterize M's unusual neuropsychological profile. We also examined the patient's and controls’ neural responses to verbal and nonverbal auditory stimuli using functional magnetic resonance imaging (fMRI). We verified that the patient exhibited persistent and severe auditory agnosia for nonverbal sounds in the absence of verbal comprehension deficits or peripheral hearing problems. Acoustical analyses suggested that his residual processing of a minority of environmental sounds might rely on his speech processing abilities. In the patient's brain, contralateral (right) temporal cortex as well as perilesional (left) anterior temporal cortex were strongly responsive to verbal, but not to nonverbal sounds, a pattern that stands in marked contrast to the controls’ data. This substantial reorganization of auditory processing likely supported the recovery of M's speech processing.