آشنایی با موضوع
بیماری آلزایمر شایع ترین نوع دمانس (خردسودگی)، با شروعی تدریجی و پیشرفتی مداوم است که به تدریج حافظه و تواناییهای ذهنی دیگر مانند تفکر، استدلال و قضاوت فرد را تحت تأثیر قرار می دهد و او در انجام وظایف روزانه زندگی با مشکل مواجه می شود. اختلال حافظه معمولاً بتدریج ایجاد شده و پیشرفت می‌کند. در ابتدا اختلال حافظه به وقایع و آموخته‌های اخیر محدود می‌شود ولی بتدریج خاطرات قدیمی هم آسیب می‌بینند. بیمار پاسخ سئوالی را که چند لحظه قبل پرسیده‌است فراموش می‌کند و مجدداً همان سؤال را می‌پرسد. بیمار وسایلش را گم می‌کند و نمی‌داند کجا گذاشته‌است. در خرید و پرداخت پول دچار مشکل می‌شود و نمی‌تواند حساب دارائیش را نگه دارد. بتدریج در شناخت دوستان و آشنایان و نام بردن اسامی آنها نیز مشکل ایجاد می‌شود. کم‌کم مشکل مسیر یابی پیدا شده و اگر تنها از منزل بیرون برود ممکن است گم شود. در موارد شدیدتر حتی در تشخیص اتاق خواب، آشپزخانه، دستشویی و حمام در منزل خودش هم مشکل پیدا می‌کند. بروز اختلال در حافظه و روند تفکر سبب آسیب عملکردهای اجتماعی و شخصی بیمار شده و در نتیجه ممکن است سبب افسردگی، عصبانیت و پرخاشگری بیمار شود. یکی از مشکلات زوال عقل بروز توهم و هذیان است. مثلاً بیمار فکر کند همسرش به وی خیانت کرده‌است و یا همسایگان و پرستارش قصد آسیب رساندن و توطئه علیه وی را دارند. بیمار ممکن است به فرزندانش بدبین شود. گاهی اوقات بیمار افرادی را که نیستند می‌بیند مثلاً والدین فوت شده یا اقوام دیگر.
در این صفحه، تعداد 151 مقاله انگلیسی از ژورنال ها و مجلات معتبر پایگاه ساینس دایرکت (ScienceDirect) درباره موضوع آلزایمر آرشیو شده است که شما می توانید مقالات مورد نظر خود را بر اساس سال انتشار، موضوع مقاله، وضعیت ترجمه و تعداد صفحات، انتخاب نموده و دانلود فرمایید.
در صورتی که مقاله لاتین مورد نظر شما تا کنون به زبان فارسی ترجمه نشده باشد، واحد ترجمه پایگاه ISI Articles با همکاری تنی چند از اساتید و مترجمان با سابقه، آمادگی دارد آن را در اسرع وقت و با کیفیت مطلوب برای شما ترجمه نماید.
در صورتی که مقاله لاتین مورد نظر شما تا کنون به زبان فارسی ترجمه نشده باشد، واحد ترجمه پایگاه ISI Articles با همکاری تنی چند از اساتید و مترجمان با سابقه، آمادگی دارد آن را در اسرع وقت و با کیفیت مطلوب برای شما ترجمه نماید.
A prognostic model of Alzheimer's disease relying on multiple longitudinal measures and time-to-event data
Power analysis to detect treatment effects in longitudinal clinical trials for Alzheimer's disease
APOE and neuroenergetics: an emerging paradigm in Alzheimer's disease
Cerebral blood volume in Alzheimer's disease and correlation with tissue structural integrity
Neuroglobin and Alzheimer's dementia: Genetic association and gene expression changes
Aerobic glycolysis and tau deposition in preclinical Alzheimer's disease
Controlled delivery of rivastigmine using transdermal patch for effective management of alzheimer's disease
Multi-class Alzheimer's disease classification using image and clinical features
Evidence for brain glucose dysregulation in Alzheimer's disease
Genetic influence of plasma homocysteine on Alzheimer's disease
The personalized Alzheimer's disease cortical thickness index predicts likely pathology and clinical progression in mild cognitive impairment
Metabolic brain networks in aging and preclinical Alzheimer's disease
Patterns of progressive atrophy vary with age in Alzheimer's disease patients
Mutation burden profile in familial Alzheimer's disease cases from India
Feasibility and efficacy data from a ketogenic diet intervention in Alzheimer's disease
Polygenic risk score in postmortem diagnosed sporadic early-onset Alzheimer's disease
Forecasting the prevalence of preclinical and clinical Alzheimer's disease in the United States
Polygenic risk for Alzheimer's disease influences precuneal volume in two independent general populations
Microbleeds are associated with depressive symptoms in Alzheimer's disease
Wellbeing, resilience, and coping: Are there differences between healthy older adults, adults with mild cognitive impairment, and adults with Alzheimer-type dementia?
Desire to institutionalize in Alzheimer's caregivers: An empirical analysis on Italian data
Impairment of memory generalization in preclinical autosomal dominant Alzheimer's disease mutation carriers
Cross domain self-monitoring in anosognosia for memory loss in Alzheimer's disease
Monoaminergic impairment in Down syndrome with Alzheimer's disease compared to early-onset Alzheimer's disease
Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts
Qualitative Analysis of Mini Mental State Examination Pentagon in Vascular Dementia and Alzheimer's Disease: A Longitudinal Explorative Study
Alzheimer's disease in humans and other animals: A consequence of postreproductive life span and longevity rather than aging
Neuroinflammation in Alzheimers disease: Pleiotropic roles for cytokines and neuronal pentraxins
The cost of Alzheimer's disease in China and re-estimation of costs worldwide
Determinants characterizing the life of a caregiver treating an individual with Alzheimer's disease
The stability of neuropsychiatric subsyndromes in Alzheimer's disease
Modeling Alzheimer's disease cognitive scores using multi-task sparse group lasso
Genetically elevated gamma-glutamyltransferase and Alzheimer's disease
Tau, amyloid, and cascading network failure across the Alzheimer's disease spectrum
Classification of Alzheimer's disease and prediction of mild cognitive impairment-to-Alzheimer's conversion from structural magnetic resource imaging using feature ranking and a genetic algorithm
Medication takeovers: Covert druggings and behavioral control in Alzheimer's
The effect of diagnostic criteria on outcome measures in preclinical and prodromal Alzheimer's disease: Implications for trial design
Prevalence and incidence of Alzheimer's disease in Europe: A meta-analysis
Multivariate analyses of peripheral blood leukocyte transcripts distinguish Alzheimer's, Parkinson's, control, and those at risk for developing Alzheimer's
Sugary beverage intake and preclinical Alzheimer's disease in the community
Longitudinal changes in microstructural white matter metrics in Alzheimer's disease
Incidence of cognitively defined late-onset Alzheimer's dementia subgroups from a prospective cohort study
Cross-validation of optimized composites for preclinical Alzheimer's disease
Homocysteine concentrations in the cognitive progression of Alzheimer's disease
Cognitive subtypes of probable Alzheimer's disease robustly identified in four cohorts
Longitudinal brain structural changes in preclinical Alzheimer's disease
Microvascular changes in Down syndrome with Alzheimer's-type pathology: Insights into a potential vascular mechanism for Down syndrome and Alzheimer's disease
Searching for new pharmacological targets for the treatment of Alzheimer's disease in Down syndrome
Cognitive reserve and the risk for Alzheimer's disease: a longitudinal study
Disentangling normal aging from Alzheimer's disease in structural magnetic resonance images
An exploratory study on STX6, MOBP, MAPT, and EIF2AK3 and late-onset Alzheimer's disease
Single time point high-dimensional morphometry in Alzheimer's disease: group statistics on longitudinally acquired data
Altered brain development in an early-onset murine model of Alzheimer's disease
Identification of PSEN1 mutations p.M233L and p.R352C in Han Chinese families with early-onset familial Alzheimer's disease
Running exercise delays neurodegeneration in amygdala and hippocampus of Alzheimer’s disease (APP/PS1) transgenic mice
Brain connectivity and novel network measures for Alzheimer's disease classification
Cannabinoid receptor 2 deficiency results in reduced neuroinflammation in an Alzheimer's disease mouse model
Cholinergic basal forebrain atrophy predicts amyloid burden in Alzheimer's disease
Hippocampal subfield volumes at 7T in early Alzheimer's disease and normal aging
Evidence of altered phosphatidylcholine metabolism in Alzheimer's disease
Psychotic Alzheimer's disease is associated with gender-specific tau phosphorylation abnormalities
Neuronal driven pre-plaque inflammation in a transgenic rat model of Alzheimer's disease
Bexarotene reduces network excitability in models of Alzheimer's disease and epilepsy
Lack of contextual-word predictability during reading in patients with mild Alzheimer disease
Dietary and lifestyle guidelines for the prevention of Alzheimer's disease
The role of synaptic activity in the regulation of amyloid beta levels in Alzheimer's disease
Time reproduction during high and low attentional tasks in Alzheimer’s Disease “A watched kettle never boils”
Genetic variation in BIN1 gene and Alzheimer's disease risk in Han Chinese individuals
Alzheimer's disease susceptibility genes APOE and TOMM40, and brain white matter integrity in the Lothian Birth Cohort 1936
Social influence on associative learning: Double dissociation in high-functioning autism, early-stage behavioural variant frontotemporal dementia and Alzheimer's disease
Detecting gene mutations in Japanese Alzheimer's patients by semiconductor sequencing