گزارش گاهشماری پلیمورفیسم مشترک در ژن سندرم ویلیامام پیش بینی واکنشگرایی و اضطراب آمیگدال در بزرگسالان سالم

A common polymorphism in the WS gene GTF2I associated with reduced social anxiety predicts decreased threat-related amygdala reactivity, which mediates an association between genotype and increased warmth in women. These results are consistent with reduced threat-related amygdala reactivity in WS and suggest that common variation in GTF2I contributes to broader variability in socioemotional brain function and behavior, with implications for understanding the neurogenetic bases of WS as well as social anxiety.