اثر متمایز عصبی-کارکردی درمان با مهارکننده های انتخابی بازدارنده سروتونین، درمان الکتروکوهانس و تحریک مغناطیسی ترانس مغناطیسی و ارتباط آنها با عملکرد مغز منطقه در افسردگی عمده: یک متاآنالیز

SSRIs and ECT produce neurally distinct effects relative to each other and to the functional abnormalities implicated in depression. These treatments therefore may exert antidepressant effects by diminishing neural functions not implicated in depression but that nonetheless impact mood. We discuss how the distinct neural changes resulting from SSRIs and ECT can account for both treatment effects and side effects from these therapies as well as how to individualize these treatments.