انتشار میکروکستهای اندوتلیال در بیماران مبتلا به فشار خون شریانی، اورژانس های فشارخون و آسیب های مرتبط با کاتتر

In arterial hypertension, increased systolic blood pressure and decreased wall shear stress (due to greater arterial diameter) are associated with the release of endothelial microparticles (EMPs). We linked this with distinct patterns of mechanical injury, activation, and endothelial dysfunction (CD62e+ and CD144+-EMPs) and decreased endothelial protection (CD31+/41--EMPs), respectively. EMPs may be part of a vicious self-perpetuating cycle involving endothelial dysfunction.Download high-res image (240KB)Download full-size image