ابزارهای میکرو با ابزارهای سوزن چرخان تحت نظارت زمان واقعی

This paper analyzes human operation of an arbitrary single micro object under 1mm while observing the object and systematically studies the design of a micro handling system to perform such operations. This system features the following mechanical elements; (1) a needle-type tool with a tip as small as the micro object to handle; (2) a palette engraved with micro structures to hold the micro object; (3) a driving mechanism not only to translate the tool but also to rotate it; (4) a microscope to observe the tool operation in real time. As the microscope occupies a large volume, the system sets the mechanism elements in a centralized arrangement so the micro object, tool tip, center of tool rotation, microscope focus intersect at one point and the remaining elements are radially arranged around it. We used this system to conduct several operations including a SEM monitored micro house construction by assembling and bonding walls and roof, an optical microscope monitored microscopic insemination by inserting a sperm into an ovum, and a fluorescent microscope monitored DNA surgery cutting out an arbitrary gene from a chromosome. These operations verified the effect of the above design guideline, that is the group of mechanism elements and their construction.