دانلود مقاله ISI انگلیسی شماره 148303
ترجمه فارسی عنوان مقاله

اصول پایه طراحی منفی در ارزیابی اثربخشی واکسن آنفلوانزا

عنوان انگلیسی
Basic principles of test-negative design in evaluating influenza vaccine effectiveness
کد مقاله سال انتشار تعداد صفحات مقاله انگلیسی
148303 2017 5 صفحه PDF
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Vaccine, Volume 35, Issue 36, 24 August 2017, Pages 4796-4800

ترجمه کلمات کلیدی
واکسن آنفلوانزا، اثربخشی، طراحی منفی تست انتخاب کنترل تست تشخیص سریع تعصب انتخابی،
کلمات کلیدی انگلیسی
Influenza vaccine; Effectiveness; Test-negative design; Control selection; Rapid diagnostic testing; Selection bias;
پیش نمایش مقاله
پیش نمایش مقاله  اصول پایه طراحی منفی در ارزیابی اثربخشی واکسن آنفلوانزا

چکیده انگلیسی

Based on the unique characteristics of influenza, the concept of “monitoring” influenza vaccine effectiveness (VE) across the seasons using the same observational study design has been developed. In recent years, there has been a growing number of influenza VE reports using the test-negative design, which can minimize both misclassification of diseases and confounding by health care-seeking behavior. Although the test-negative designs offer considerable advantages, there are some concerns that widespread use of the test-negative design without knowledge of the basic principles of epidemiology could produce invalid findings. In this article, we briefly review the basic concepts of the test-negative design with respect to classic study design such as cohort studies or case-control studies. We also mention selection bias, which may be of concern in some countries where rapid diagnostic testing is frequently used in routine clinical practices, as in Japan.