نمره ریسک بیماری پولی ژنیک در بیمار مبتلا به آلزایمر که به تازگی مبتلا شده است، یک معماری مشترک با فرم های خانوادگی و زودهنگام را نشان می دهد

Our analysis confirms that the genetic factors identified for LOAD modulate risk in sLOAD and fLOAD and also sEOAD cohorts. Specifically, our results suggest that the burden of these risk variants is associated with familial clustering and earlier onset of AD. Although these variants are not associated with risk in the eADAD, they may be modulating age at onset.