بهبود عملکرد در عبور قشری و زبن پریشی استاندارد

Our aim was to investigate functional recovery in two anomic patients with subcortical aphasia, one crossed aphasia and one standard, uncrossed aphasia due to a similar subcortical lesion. An er-fMRI follow-up paradigm was employed during a picture-naming task. Both patients were scanned prior to speech therapy (T0), after 3 months of anomia-specific rehabilitation (T1) and following 6 months of conventional language rehabilitation (T2). Irrespectively of lesion lateralization, fMRI data disclosed a grounding role for homologue naming-specific areas (respectively, LIFG and RIFG) in determining the progressive pattern of behavioural naming recovery throughout different disease phases. Thus, functional recovery, parallelled by improvement in behavioural naming performance, seems to be strictly related to recruitment of homologue areas in the hemisphere opposite to the aphasiogenic lesion.