دانلود مقاله ISI انگلیسی شماره 29889
ترجمه فارسی عنوان مقاله

تکانشگری، پرخاشگری و ساختار مغز در اقدام کننده به خودکشی مرگ آوری کم و زیاد با اختلال شخصیت مرزی

عنوان انگلیسی
Impulsivity, aggression and brain structure in high and low lethality suicide attempters with borderline personality disorder
کد مقاله سال انتشار تعداد صفحات مقاله انگلیسی
29889 2014 9 صفحه PDF
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Psychiatry Research: Neuroimaging, Volume 222, Issue 3, 30 June 2014, Pages 131–139

ترجمه کلمات کلیدی
- تصویربرداری رزونانس مغناطیسی - ضربه تهاجمی - رفتار خودکشی - اختلال شخصیت مرزی -
کلمات کلیدی انگلیسی
Magnetic resonance imaging, Impulsive–aggression,Suicidal behavior,Borderline personality disorder,
پیش نمایش مقاله
پیش نمایش مقاله  تکانشگری، پرخاشگری و ساختار مغز در اقدام کننده به خودکشی مرگ آوری کم و زیاد با اختلال شخصیت مرزی

Impulsivity and aggressiveness are trait dispositions associated with the vulnerability to suicidal behavior across diagnoses. They are associated with structural and functional abnormalities in brain networks involved in regulation of mood, impulse and behavior. They are also core characteristics of borderline personality disorder (BPD), a disorder defined, in part, by recurrent suicidal behavior. We assessed the relationships between personality traits, brain structure and lethality of suicide attempts in 51 BPD attempters using multiple regression analyses on structural MRI data. BPD was diagnosed by the Diagnostic Interview for Borderline Patients-revised, impulsivity by the Barratt Impulsiveness Scale (BIS), aggression by the Brown–Goodwin Lifetime History of Aggression (LHA), and high lethality by a score of 4 or more on the Lethality Rating Scale (LRS). Sixteen High Lethality attempters were compared to 35 Low Lethality attempters, with no significant differences noted in gender, co-morbidity, childhood abuse, BIS or LHA scores. Degree of medical lethality (LRS) was negatively related to gray matter volumes across multiple fronto-temporal–limbic regions. Effects of impulsivity and aggression on gray matter volumes discriminated High from Low Lethality attempters and differed markedly within lethality groups. Lethality of suicide attempts in BPD may be related to the mediation of these personality traits by specific neural networks.