مدل سازی واکنش بین نورون ها و استروسیت ها در مبتلایان به اوتیسم با استفاده از سلول های بنیادی انعقادی انسانی

Our findings reveal the contribution of astrocytes to neuronal phenotype and confirm previous studies linking interleukin-6 and autism, suggesting potential novel therapeutic pathways for a subtype of individuals with ASD. This is the first report demonstrating that glial dysfunctions could contribute to nonsyndromic autism pathophysiology using induced pluripotent stem cells modeling disease technology.