کمبود لکتین ناشی از انسولین اتوزومی مغذی همراه با نتایج بدتر از پیشرفت های عصبی پس از عمل جراحی قلب در نوزادان

We report the novel finding that carriers of MBL2Gly54Asp causing autosomal dominant MBL deficiency have increased childhood pervasive developmental problems after cardiac surgery, independent of other covariates. Sensitivity analyses suggest that this effect may be larger in children who underwent surgery at earlier ages. These data support the role of nonsyndromic genetic variation in determining postsurgical neurodevelopment-related outcomes in children with congenital heart disease.