گروه کنترل فعال دارونما از مداخلات فارماکولوژیک به ندرت مورد استفاده قرار گرفت اما مورد توجه جدی قرار گرفت: یک مرور روش شناختی

Pharmacological active placebo control interventions are rarely used in randomized clinical trials, but they constitute a methodological tool which merits serious consideration. We suggest that active placebos are used more often in trials of drugs with noticeable side effects, especially in situations where the expected therapeutic effects are modest and the risk of bias due to unblinding is high.