نقاط عطف رشد اولیه و اسکیزوفرنی: بررسی منظم و متاآنالیز

The following motor milestones were significantly associated with adult schizophrenia risk: walking unsupported (g = 0.46; 95% CI 0.27–0.64; p < 0.001), standing unsupported (g = 0.28; 0.16–0.40; p < 0.001) and sitting unsupported (g = 0.18; 0.05–0.31; p = 0.007). Results for the milestones ‘holding head up’ and ‘grabbing object’ were not statistically significant. Delayed walking, sitting and standing unsupported were associated with adult onset schizophrenia. The findings emphasise the importance of timely achievement of these motor milestones in childhood and can contribute to the identification of individuals at risk of psychosis.