دانلود مقاله ISI انگلیسی شماره 69827
ترجمه فارسی عنوان مقاله

واکنش های فیزیولوژی عصبی تغییر داده شده به چهره عاطفی کودکان مبتلا به ASD، ADHD و ASD + ADHD را متمایز می کند

عنوان انگلیسی
Altered neurophysiological responses to emotional faces discriminate children with ASD, ADHD and ASD + ADHD
کد مقاله سال انتشار تعداد صفحات مقاله انگلیسی
69827 2014 10 صفحه PDF
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Biological Psychology, Volume 103, December 2014, Pages 125–134

ترجمه کلمات کلیدی
ASD؛ بیش فعالی؛ همبودی؛ هیجانی؛ پتانسیل های مرتبط با رویداد (ERP)
کلمات کلیدی انگلیسی
ASD; ADHD; Comorbidity; Emotion; Event-related potentials (ERP)
پیش نمایش مقاله
پیش نمایش مقاله  واکنش های فیزیولوژی عصبی تغییر داده شده به چهره عاطفی کودکان مبتلا به ASD، ADHD و ASD + ADHD را متمایز می کند

چکیده انگلیسی

There are high rates of overlap between autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD). Emotional impairment in the two disorders, however, has not been directly compared using event-related potentials (ERPs) that are able to measure distinct temporal stages in emotional processing. The N170 and N400 ERP components were measured during presentation of emotional face stimuli to boys with ASD (n = 19), ADHD (n = 18), comorbid ASD + ADHD (n = 29) and typically developing controls (n = 26). Subjects with ASD (ASD/ASD + ADHD) displayed reduced N170 amplitude across all stimuli, particularly for fearful versus neutral facial expressions. Conversely, subjects with ADHD (ADHD/ASD + ADHD) demonstrated reduced modulation of N400 amplitude by fearful expressions in parietal scalp regions and happy facial expressions in central scalp regions. These findings indicate a dissociation between disorders on the basis of distinct stages of emotion processing; while children with ASD show alterations at the structural encoding stage, children with ADHD display abnormality at the contextual processing stage. The comorbid ASD + ADHD group presents as an additive condition with the unique deficits of both disorders. This supports the use of objective neural measurement of emotional processing to delineate pathophysiological mechanisms in complex overlapping disorders.