شیدایی زیرآستانه ای به عنوان پیش بینی کننده افسردگی در طول درمان اینترفرون در بیماران مبتلا به HCV بدون اختلالات روانپزشکی فعلی و یا اختلال طول عمر

Our data suggest that individuals treated with IFN with no past history of psychiatric disorders are more likely to develop depression if they experienced subthreshold manic–hypomanic symptoms in their lifetime. These findings derive from an exploratory study and may have important implications for the prevention of IFN-induced depression if replicated in larger studies.