پلی مورفیسم ژنتیکی مربوط به رویکرد رفتاری و معیارهای بازداری رفتاری

Genetic polymorphisms relevant to behavioral approach and behavioral inhibition are examined, using a polygenic approach while also considering the role of early adversity. Undergraduates (N = 343) completed the well-validated Behavioral Inhibition System/Behavioral Activation System (BIS/BAS) scales and provided blood for genotyping. The BDNF met allele was related to higher BIS scores. OPRM1 status interacted with a measure of early adversity to predict the BAS Reward Responsiveness subscale. Results provide additional support for the validity of the BIS/BAS scales, and suggest combined genetic and environmental influences on the development of these traits.