تاثیر تغییر در ژن BDNF بر حساسیت استرس اجتماعی و تاثیر میانجیگری هیجانات مثبت: تکرار و گسترش تعامل ژن-محیط زیست

In conclusion, ESM has important advantages in gene–environment (GxE) research and may attribute to more consistent findings in future GxE research. This study shows how the impact of BDNF genetic variation on depressive symptoms may be explained by its impact on subtle daily life responses to social stress. Further, it shows that the generation of positive affect (PA) can buffer social stress sensitivity and partially undo the genetic susceptibility.