عملکرد شناختی و الگوهای مصرف مواد مخدر در میان مصرف کنندگان کوکائین آغاز و در اواخر شروع شده است

Early-onset cocaine users display more pronounced neuropsychological alterations than controls, as well as a greater frequency of polydrug consumption than LOG. The prominent cognitive deficits in EOG probably reflect the deleterious interference of cocaine use with early stages of neurodevelopment. This may be related to more severe clinical characteristics of substance disorder in this subgroup, including polysubstance abuse.