دانلود مقاله ISI انگلیسی شماره 33487
ترجمه فارسی عنوان مقاله

لکنت زبان و مدارهای گانگلیون بازال: نقد و ارتباط احتمالی

عنوان انگلیسی
Stuttering and the basal ganglia circuits: a critical review of possible relations
کد مقاله سال انتشار تعداد صفحات مقاله انگلیسی
33487 2004 45 صفحه PDF
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Journal of Communication Disorders, Volume 37, Issue 4, July–August 2004, Pages 325–369

ترجمه کلمات کلیدی
لکنت زبان - گانگلیون بازال - دوپامین - دیستونیا -
کلمات کلیدی انگلیسی
Stuttering; Basal ganglia; Dopamine; Dystonia; Cluttering
پیش نمایش مقاله
پیش نمایش مقاله  لکنت زبان و مدارهای گانگلیون بازال: نقد و ارتباط احتمالی

The possible relation between stuttering and the basal ganglia is discussed. Important clues to the pathophysiology of stuttering are given by conditions known to alleviate dysfluency, like the rhythm effect, chorus speech, and singing. Information regarding pharmacologic trials, lesion studies, brain imaging, genetics, and developmental changes of the nervous system is reviewed. The symptoms of stuttering are compared with basal ganglia motor disorders like Parkinson’s disease and dystonia. It is proposed that the basal ganglia-thalamocortical motor circuits through the putamen are likely to play a key role in stuttering. The core dysfunction in stuttering is suggested to be impaired ability of the basal ganglia to produce timing cues for the initiation of the next motor segment in speech. Similarities between stuttering and dystonia are indicated, and possible relations to the dopamine system are discussed, as well as the interaction between the cerebral cortex and the basal ganglia. Behavioral and pharmacologic information suggests the existence of subtypes of stuttering.