دانلود مقاله ISI انگلیسی شماره 71433
ترجمه فارسی عنوان مقاله

به روز رسانی اطلاعات متنی در طول تثبیت حافظه به عنوان نتیجه ردیابی حافظه جدید

عنوان انگلیسی
Updating contextual information during consolidation as result of a new memory trace
کد مقاله سال انتشار تعداد صفحات مقاله انگلیسی
71433 2010 11 صفحه PDF
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Neurobiology of Learning and Memory, Volume 93, Issue 4, May 2010, Pages 561–571

ترجمه کلمات کلیدی
به روز رسانی حافظه؛ تثبیت؛ حافظه کوتاه مدت؛ مجدد
کلمات کلیدی انگلیسی
Memory update; Consolidation; Short-term memory; Reconsolidation
پیش نمایش مقاله
پیش نمایش مقاله  به روز رسانی اطلاعات متنی در طول تثبیت حافظه به عنوان نتیجه ردیابی حافظه جدید

چکیده انگلیسی

Reconsolidation studies have led to the hypothesis that memory, when labile, would be modified in order to incorporate new information. This view has reinstated original propositions suggesting that short-term memory provides the organism with an opportunity to evaluate and rearrange information before storing it, since it is concurrent with the labile state of consolidation. The Chasmagnathus associative memory model is used here to test whether during consolidation it is possible to change some attribute of recently acquired memories. In addition, it is tested whether these changes in behavioral memory features can be explained as modifications on the consolidating memory trace or as a consequence of a new memory trace. We show that short-term memory is, unlike long-term memory, not context specific. During this short period after learning, behavioral memory can be updated in order to incorporate new contextual information. We found that, during this period, the cycloheximide retrograde amnesic effect can be reverted by a single trial in a new context. Finally, by means of memory sensitivity to cycloheximide during consolidation and reconsolidation, we show that the learning of a new context (CS) during this short-term memory period builds up a new memory trace that sustains the behavioral memory update.